Experimental autoimmune hearing loss

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Experimental autoimmune hearing loss

1114 The Journal of Clinical Investigation http://www.jci.org Volume 113 Number 8 April 2004 expression and restores sterol sensing (Figure 1). Upon fasting, Insig-2a levels rise, suppressing lipogenesis in a sterol-dependent fashion. Insulin cycling might be critical for the prevention of excessive lipogenesis. It creates a brief window during refeeding when Insig levels begin to decline and t...

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A Choline Transporter and Autoimmune Hearing Loss

Antibodies to neural antigens cause several neurological diseases, myasthenia gravis with its acetylcholine receptor antibodies being perhaps the best known. Autoimmune damage is also suspected as a cause of rapidly progressive hearing loss. In this issue, Nair et al. track down the antigen underlying hearing loss that is caused by an antibody (KHRI-3) generated against the guinea pig organ of ...

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Autoimmune hearing loss and ulcerative colitis.

This is a male 23-year-old patient presenting with right tinnitus, ipsilateral hypoacusis and dizziness following three months of diarrhea and weight loss. The patient was taking deflazacort and budesonide, which improved his intestinal, hearing and postural symptoms, but not the tinnitus. Initial audiometry revealed mild right sensorineural dysacusis. Laboratory exams included a positive ANF, ...

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P 83: Progression of Hearing Loss in Experimental Meningitis

Hearing loss and meningitis were correlate in some aspects. Hearing loss is the situation that can be shown in cochlear or retrocochlear defects. Cochlear hearing loss is caused by inner or outer hair cell damage (however cochlear hearing loss has another causes, such as defect of arterial spiral ganglion, basilar and tectorial membrane) and retrocochlear hearing loss has neural origin and meni...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 2004

ISSN: 0021-9738

DOI: 10.1172/jci21632